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2004年からの業績


1.    Sato K., Sugiyama T., Nagase T., Kitade Y., and Ueda H. Threonine 680 phosphorylation of FLJ00018/PLEKHG2, a Rho family-specific guanine nucleotide exchange factor, by epidermal growth factor receptor signaling regulates cell morphology of Neuro-2a cells. J. Biol. Chem., in press (2014)

2.   
Kheirollah A., Nagayasu Y., Ueda H., Yokoyama S., Michikawa M., andvIto JI. Involvement of cdc42/Rho kinase in ApoA-I-mediated cholesterol efflux through interaction between cytosolic lipid-protein particles and microtubules in rat astrocytes. J. Neurosci. Res., in press (2014)


3.    Sato K., Suzuki T., Yamaguchi Y., Kitade Y., Nagase T. and Ueda H., PLEKHG2/FLJ00018, a Rho family-specific guanine nucleotide exchange factor, is tyrosine phosphorylated via the EphB2/cSrc signaling pathway. Cell. Signal in press (2014)

4.    Kimura S., Sato K., Banno Y., Nagase T. and Ueda H. The importance of interaction with membrane lipids through the pleckstrin homology domain of the guanine nucleotide exchange factor for Rho family small GTPase, FLJ00018 Biol. Pharma. Bull. 36: 1204-1207 (2013)

5.    Sato K., Handa H., Kimura M, Okano Y., Nagaoka H., Nagase T., Sugiyama T. Kitade Y. and Ueda H. Identification of Rho family specific guanine nucleotide exchange factor, FLJ00018 as a novel actin-binding protein. Cell. Signal. 25: 41-49 (2013)

6.    榊原清美、遠藤亜希子、田中史帆、長瀬隆弘、上田浩、今枝孝夫、嗅覚受容体応答とヒトの嗅覚閾値との相関 日本味と匂学会誌  19: 433 -436 (2012) 平成25年度味と匂いの学会論文賞受賞

7.    Sugiyama T., Gotou T., Moriyama K., Nodoka Kajiura K., Hasegawa T., Tomida J., Takahashi K., Komatsu T., Ueda H., Sato K., Tokoro S., Neri P. and Mori H. Mechanism of inhibition of lipopolysaccharide-induced interferon- production by 2-aminopurine. Mol. Immun. 52:299-304. (2012).

8.    Yasui Y., Miyazawa D., Hiroshi Ueda H., Sato K., Kitade Y. and Yamada K. PMA-induced GCMa phosphorylation stimulates its transcriptional activity and degradation. Biomed. Res. 33:217-224. (2012)

9.    Yasui Y., Yamada K., Takahashi S., Sugiura-Ogasawara M., Sato K., Miyazawa D., Sugiyama T., Kitade Y., and Ueda H.  PMA induces GCMa phosphorylation and alters its stability via the PKC- and ERK-dependent pathway. Biochem. Biophys. Res. Commun. 417:1127-1132. (2012).

10.    Nagae R., Sato K., Yasui Y., Banno Y., Nagase T. and Ueda H. Gs and Gq signalings regulate hPEM-2-induced cell responses in Neuro-2a cells. Biochem. Biophys. Res. Commun. 415:168-204. (2011).

11.  Koike C., Numata T., Ueda H., Mori Y. and Furukawa T. TRPM1: A vertebrate TRP channel responsible for retinal ON bipolar function. Cell Calucium. 48: 95-101 (2010) 総説

12. 
Koike C., Obara T., Uriu Y., Numata T., Sanuki R., Miyata K., Koyasu T., Ueno S., Funabiki K., Tani A., Ueda H., Kondo M., Mori Y., Tachibana M. and Furukawa T.  TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade.  Proc. Natl. Acad.Sci. U. S. A. 107: 332-337 (2010) Faculty of 1000 recommended

13.  Nemoto S., Nakamura M., Osawa Y., Kono S., Itoh Y., Okano Y., Murate T., Hara A., Ueda H., Nozawa Y., and Banno Y.  Sphingosine kinase isoforms regulate oxaliplatin sensitivity of human colon cancer cells through ceramide accumulation and AKT activation. J. Biol. Chem. 284: 10422-10432 (2009).

14.  Yoshida S., Okazaki Y., Yamashita T., Ueda H., Ghadimi R., Hosono A., Tanaka T., Kuriki K., Suzuki S., and Tokudome S. Analysis of human oral mucosa ex vivo for fatty acid compositions using Fourier-transform infrared spectroscopy. Lipids 43: 361-372 (2008 )

15.  Ueda H., Nagae R., Kozawa M., Morishita R., Kimura S., Nagase T., Ohara O., Yoshida S. and Asano T. Heterotrimeric G Protein bg Subunits Stimulate FLJ00018, a Guanine Nucleotide Exchange Factor for Rac1 and Cdc42. J. Biol. Chem. 283: 1946-1953 (2008). Faculty of 1000 recommended


16.  Morishita R., Ueda H., Ito, H., Takasaki, J., Nagata, K., and Asano, T. Invilvement of Gq/11 in both integrin signal-dependent and –independent pathways regulating endotheline-induced neural progenitor proliferation. Neurosci. Res. 59: 205-214 (2007)

17.  Tanaka Y., Yoshida S., Shimada Y., Ueda H., and Asai K., Aslterration in serum neural cell adhesion molecule in patients of schizophrenia. Human Psychopharmacol.  22:97-102 (2007)

18.  Morishita R., Nagata K., Ito H., Ueda H., Asano M., Shinohara H., Kato K., and Asano T.,  Expression of Smooth Muscle Cell-specific Proteins in Neural Progenitor Cells Induced by Agonists of G Protein-coupled Receptors and Transforming Growth Factor-β, J. Neurochem. 101: 1031-1040 (2007)

19.  Ito H., Ueda H., Iwamoto I., ,Inaguma Y., Takizawa T., Asano T., and Kato K.  Nordihydroguaiaretic acid (NDGA) blocks the differentiation of C2C12 myoblast cells, J. Cell. Physiol. 202, 874-879 (2005)

20.  Shinohara H., Udagawa J., Morishita R., Ueda H., Otani H., Semba R., Kato K., and Asano T.  Gi2 Signaling Enhances Proliferation of Neural Progenitor Cells in the Developing Brain. J. Biol. Chem. 279: 41141 - 41148 (2004)

21. Ueda H., Morishita R., Narumiya S., Kato K., and Asano T. Gq/11 signaling induces apoptosis through two pathways involving reduction of Akt phosphorylation and activation of RhoA in HeLa cells. Exp. Cell Res. 298: 207-217 (2004)

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